Issues Vol. 19 No. 3

Foreword (10k)
BAS as Darwin Might See Us...

Electrochemical Techniques for the Characterization of Redox Polymers (57k)
Adrian Bott of Bioanalytical Systems, Inc. discusses the different electroanalytical techniques that have been used to characterize redox polymers immo-bilized on electrode surfaces.

Simplified Methods of Determining Co(II) and Ni(II) in Aqueous Samples (32k)
An approach to simplifying the adsorptive stripping voltammetric determination of Co (II) and Ni (II) by H. G. Jayaratna.

Interstitial Fluid Calcium, Magnesium and Phosphorus Concentrations in Bone, Muscle and Subcutaneous Tissue Sampled with Ultrafiltration Probes (39k)
Elsa Janle and Melony Cregor of BASi and Janice Sojka of Purdue University’s Veterinary School discuss use of specialized ultrafiltration probes to measure calcium, magnesium and phosphorus in sheep.

Drug Metabolism and Pharmacokinetics in Drug Discovery: A Primer For Bioanalytical Chemists, Part II (99k)
In this second of a 2-part series, Chandrani Gunaratna introduces the analytical chemist to the pharmacokinetics of in vitro drug metabolism data.

Products, In the EC Literature, In the MD Literature, Miscellany (121k)
In the EC Literature: Adrian Bott of BASi summarizes papers on EC properties of natural carote-noids, monolayer enzyme electrodes, an injection EC biosensor, imidazolate-bridged dinuclear complexes, and oxidation of zuclopenthixol.
In the LC Literature: Bruce Solomon of BASi reviews papers on chronic morphine treatment, and withdrawal and dopamine levels in freely-moving rats.
In the MD Literature: James Gitzen of BASi discusses papers on potassium permanganate in brain microdialysis, a study of the effects of handling stress in the rat brain, and microdialysis sampling of isothiazolone.
MD Q & A: James Gitzen of BASi answers questions about MWCOs.
Technical Note: Melony Cregor and Bruce Solomon of BASi discuss BASi Culex ® and The Effect of Blood-Drawing Method on Plasma Catecholamine Concentrations in Rats.
Miscellany: Beijing Conference, Peter Kissinger: Scientist, Entrepreneur, and “still basically twelve years old.”
BASI News: A progress report on marketing the new BASi Culex ® Automated Blood Sampler and other recent developments at BAS.